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Article

Analysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2-positive patients with insulin-dependent diabetes mellitus.

Tissue antigens - 1 Aug 1994

Sanjeevi C B, Lybrand T P, Landin-Olsson M, Kockum I, Dahlquist G, Hagopian W A, Palmer J P, Lernmark A

Abstract excerpt

HLA-DR2 is negatively associated with insulin-dependent diabetes mellitus (IDDM). The aim of the present study was to analyze DR2-positive patients among 425 consecutively diagnosed unrelated Swedish children with IDDM and in 367 matched controls. HLA-DRB, -DQA and -DQB were determined by Taq I restriction fragment length polymorphism analysis. Amplification by polymerase chain reaction (PCR) and hybridization...

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Identifiers

PMID: 7817375
DOI: 10.1111/j.1399-0039.1994.tb02366.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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