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Article

DNA polymorphism analysis of HLA class II genes in unrelated children and in first-degree relatives with type I diabetes.

Diabetes research (Edinburgh, Scotland) - 1 Oct 1991

Jos J, Farkas D, de Tand M F, Cartron J, Cohen-Hagenhauer O, Tozzo E, Deschamps I

Abstract excerpt

Eighty unrelated diabetic children, seventy healthy controls and hundred and ten affected and unaffected first-degree relatives of twenty multiplex families were investigated by restriction fragment length polymorphism analysis of HLA class II genes using five probe/enzyme systems: DRB and DQB/Taq I, DRB and DQB/EcoRI and DQB/BamHI according to standard procedures described in the 10th Histocompatibility Workshop...

Topics

Adolescent
Alleles
Child
DNA
Diabetes Mellitus, Type 1
Family
Female
Genes, MHC Class II
HLA-A Antigens
HLA-B Antigens
HLA-C Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Haplotypes

Humans

Male

Polymorphism, Restriction Fragment Length

Reference Values

Source

Identifiers

PMID: 1688161

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1688161-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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