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Article

HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families.

Tissue antigens - 1 Aug 2003

Hermann R, Turpeinen H, Laine A P, Veijola R, Knip M, Simell O, Sipilä I, Akerblom H K, Ilonen J

Abstract excerpt

The diabetes predisposing effect of HLA genes is defined by a complex interaction of various haplotypes. We analyzed the disease association of HLA DRB1-DQA1-DQB1 genotypes in a large nuclear family cohort (n = 622) collected in Finland. Using the affected family based artificial control approach we aimed at characterizing all detectable disease-specific HLA haplotype and genotype effects. The DRB1*0401-DQB1*0302...

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Source

Identifiers

PMID: 12889996
DOI: 10.1034/j.1399-0039.2003.00071.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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