Reversal of multidrug resistance by RU 486.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Reversal of multidrug resistance by RU 486.

Cancer research - 15 Jun 1994

Gruol D J, Zee M C, Trotter J, Bourgeois S

Abstract excerpt

P-Glycoproteins represent a family of drug efflux proteins that convey multidrug resistance to cells in which they are expressed. This phenomenon can lower the efficacy of drugs used in chemotherapy. The steroid progesterone has been shown to bind P-glycoproteins and inhibit their drug efflux. We...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
Antineoplastic Agents
Carrier Proteins
Colchicine
Daunorubicin
Dexamethasone
Drug Resistance
Female
Kinetics
Membrane Glycoproteins
Mice
Mice, Inbred BALB C
Mifepristone
Phenotype
Puromycin
Structure-Activity Relationship
Thymoma

Source

Open in PubMed

Identifiers

PMID: 7911394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7911394-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics