Article
Flow cytometric evaluation of multidrug-resistance circumvention.
Bulletin du cancer - 1 Jan 1995
Léonce S, Pierré A, Atassi G
Abstract excerpt
Flow cytometry, through the measurement of P-gp expression and function, is an important tool in the characterization of multidrug resistant cell lines used in pharmacology. Furthermore, as a complement to classical in vitro tests, this technique allows rapid evaluation of the capacity of new modulator agents to reverse the resistance to cytotoxic drugs and contributes a deeper insight into the mechanism of...
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