Article
Multidrug resistance phenotype evaluation by immunofluorescence and functional tests: comparison of two monoclonal antibodies and three fluorescent dyes in three cells lines.
Anticancer research - 1 Jan 2000
Maynadie M, Lizard G, Solary E, Roignot P, Carli P M
Abstract excerpt
Various agents have been shown to enhance drug sensitivity of multidrug resistant (MDR) cells and are thus of interest when the MDR phenotype is identified. Detection of MDR cells is of importance and can be carried out either by immunofluorescence with monoclonal antibodies or by functional test...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 1
- Antibodies, Monoclonal
- Benzimidazoles
- Cell Line
- Daunorubicin
- Doxorubicin
- Drug Resistance, Multiple
- Female
- Flow Cytometry
- Fluorescent Antibody Technique
- Fluorescent Dyes
- Humans
- Leukemia, Erythroblastic, Acute
- Phenotype