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Article

Genetic polymorphisms of the non-obese diabetic (NOD) mouse.

Immunology and cell biology - 1 Apr 1994

McClive P J, Baxter A G, Morahan G

Abstract excerpt

The non-obese diabetic (NOD) mouse is a polygenic model of insulin-dependent diabetes. To better understand the biology, immunology and genetics of this mouse strain NOD mice were typed for RFLP at 29 loci and microsatellite variation at a further nine loci. Mice were also typed for the expression of lymphocyte differentiation antigens. Comparisons were made with two non-diabetic strains, C57BL/6 and SJL, for...

Topics

Alleles
Animals
Antigens, CD
Antigens, Differentiation, B-Lymphocyte
Antigens, Differentiation, T-Lymphocyte
DNA Probes
Diabetes Mellitus, Type 1
Genetic Variation
Genotype
Immunophenotyping
Lymph Nodes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mice, Inbred NOD

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 7911121
DOI: 10.1038/icb.1994.21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7911121-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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