Article
Dissecting genetic control of autoimmunity in NOD congenic mice.
Immunologic research - 1 Jan 2006
Ridgway William M
Abstract excerpt
My lab investigates genetic control of autoimmune disease and autoimmune phenotypes using a series of nonobese diabetic (NOD) congenic mice. NOD congenic mice have regions from B6/B10 introgressed onto the NOD genetic background, which reduces the severity/incidence of autoimmune diabetes. We have demonstrated, however, that while diabetes is reduced, other autoimmune phenotypes and diseases arise in NOD congenic...
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