Article
Intestinal differentiation and p53 gene alterations in Barrett's esophagus and esophageal adenocarcinoma.
International journal of cancer - 15 Feb 1994
Moore J H, Lesser E J, Erdody D H, Natale R B, Orringer M B, Beer D G
Abstract excerpt
The development of esophageal adenocarcinoma is frequently associated with intestinal-type Barrett's metaplasia. Barrett's metaplasia and esophageal adenocarcinomas were examined for expression of the intestinal brush-border-associated hydrolase aminopeptidase N (APN). APN mRNA was detected by ut...
Topics
- Adenocarcinoma
- Aminopeptidases
- Barrett Esophagus
- Base Sequence
- CD13 Antigens
- Esophageal Neoplasms
- Gene Expression
- Genes, p53
- Humans
- Intestinal Mucosa
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- RNA, Messenger