Article

Abnormal<i>TP53</i>predicts risk of progression in patients with Barrett’s esophagus regardless of a diagnosis of dysplasia

2020-10-21

Abstract excerpt

<h4>ABSTRACT</h4> Barrett’s esophagus is the precursor to esophageal adenocarcinomas, which are deadly cancers with a rapidly rising incidence. A major challenge is identifying the small group with Barrett’s esophagus who will progress to advanced disease from the many who will not. Assessment of p53 status has promise as a predictive biomarker, but analytic limitations and lack of validation in large, definitive...

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Literature Corpus work: ff3d6b39-71e5-526a-b84e-aba61d61ae52
DOI: 10.1101/2020.10.18.20213561

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