Article
p53 immunoreactivity in Barrett's metaplasia, dysplasia, and adenocarcinoma--a case report.
Hepato-gastroenterology - 1 Jan 2000
Kimura H, Konishi K, Kaji M, Maeda K, Yabushita K, Miwa A
Abstract excerpt
Barrett's esophagus is a condition in which the stratified squamous epithelium of the esophagus is replaced by a columnar epithelium with malignant potential. Mutations of the tumor-suppressor gene p53 have been implicated in the evolution of esophageal carcinomas. The aim of this study was to determine whether p53 immunoreactivity in Barrett's esophagus is a marker of neoplasia and, if so, when it occurs in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
