Article
Overexpression of p53 protein in Barrett's syndrome with malignant transformation.
Journal of clinical pathology - 1 Apr 1993
Fléjou J F, Potet F, Muzeau F, Le Pelletier F, Fékété F, Hénin D
Abstract excerpt
AIMS: To study the overexpression of p53 protein in Barrett's oesophagus with adenocarcinoma, and to correlate this expression with the pathological features of Barrett's syndrome. METHODS: Immunohistochemical staining was performed on frozen sections with a monoclonal antibody directed against wild type and mutated p53 protein (Pab 1801). Eleven cases of Barrett's adenocarcinoma were studied, seven of which had...
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