Article
Mutations of p53 in Barrett's esophagus and Barrett's cancer: a prospective study of ninety-eight cases.
The Journal of thoracic and cardiovascular surgery - 1 Feb 1996
Schneider P M, Casson A G, Levin B, Garewal H S, Hoelscher A H, Becker K, Dittler H J, Cleary K R, Troster M, Siewert J R, Roth J A
Abstract excerpt
We had previously identified p53 mutations in Barrett's esophagus and therefore began a multiinstitutional study to determine their significance as a marker for malignancy. Ninety-eight patients from four institutions were studied. Forty-eight patients (37 men and 11 women, mean age 56.2 years) had Barrett's esophagus with metaplasia or dysplasia but no evidence of malignancy at a mean follow-up of 2.2 years....
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