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Article

p53 gene mutation and protein accumulation during neoplastic progression in Barrett's esophagus.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2001

Bian Y S, Osterheld M C, Bosman F T, Benhattar J, Fontolliet C

Abstract excerpt

The aim of the present study was to characterize expression and mutation of p53 during the neoplastic progression from Barrett's esophagus to adenocarcinoma and to test the reliability of immunohistochemistry for p53 overexpression as an indicator of p53 mutation in this context. The association of both gene mutation and protein accumulation with clinicopathological findings and survival was also studied. A total...

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Source

Identifiers

PMID: 11353048
DOI: 10.1038/modpathol.3880324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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