Article
Barrett's esophagus. The significance of p53 in clinical practice.
Annals of surgery - 1 Jan 1997
Ireland A P, Clark G W, DeMeester T R
Abstract excerpt
OBJECTIVE: The authors provide an updated review the molecular biology of the p53 tumor suppressor gene with reference to its role in the malignant degeneration of Barrett's esophagus. SUMMARY BACKGROUND DATA: Appreciation of the function of the tumor suppressor gene p53 has given new insight into regulation of the cell cycle, and the gene appears to play an important role in many solid tumors. Esophageal...
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