Article
Barrett's esophagus. The significance of p53 in clinical practice.
Annals of surgery - 1 Jan 1997
Ireland A P, Clark G W, DeMeester T R
Abstract excerpt
OBJECTIVE: The authors provide an updated review the molecular biology of the p53 tumor suppressor gene with reference to its role in the malignant degeneration of Barrett's esophagus. SUMMARY BACKGROUND DATA: Appreciation of the function of the tumor suppressor gene p53 has given new insight int...
Topics
- Adenocarcinoma
- Barrett Esophagus
- Cell Transformation, Neoplastic
- Esophageal Neoplasms
- Gene Expression Regulation
- Genes, p53
- Humans
- Mutation