Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization.

doi:10.1128/iai.63.4.1573-1580.1995

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Article

Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization.

Infection and immunity - 1 Apr 1995

Sadziene A, Thomas D D, Barbour A G

Abstract excerpt

All Borrelia burgdorferi sensu lato isolates characterized to date have one or a combination of several major outer surface proteins (Osps). Mutants of B. burgdorferi lacking Osps were selected with polyclonal or monoclonal antibodies at a frequency of 10(-6) to 10(-5). One mutant that lacked Osp...

Topics

Animals
Antibodies, Bacterial
Antibodies, Monoclonal
Antigens, Bacterial
Antigens, Surface
Bacterial Adhesion
Bacterial Outer Membrane Proteins
Bacterial Vaccines
Borrelia burgdorferi Group
Female
Immunologic Techniques
Lipoproteins
Mice
Mice, Inbred C3H
Mutation
Skin

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