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Article

Borrelia burgdorferi mutant lacking Osp: biological and immunological characterization.

Infection and immunity - 1 Apr 1995

Sadziene A, Thomas D D, Barbour A G

Abstract excerpt

All Borrelia burgdorferi sensu lato isolates characterized to date have one or a combination of several major outer surface proteins (Osps). Mutants of B. burgdorferi lacking Osps were selected with polyclonal or monoclonal antibodies at a frequency of 10(-6) to 10(-5). One mutant that lacked OspA, -B, -C, and -D was further characterized. It was distinguished from the OspA+B+ cells by its (i) autoaggregation and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 7890424
DOI: 10.1128/iai.63.4.1573-1580.1995
PMCID: PMC173191

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