Article
Phenotypic analysis of outer surface protein C (OspC) of Borrelia burgdorferi sensu lato by monoclonal antibodies: relationship to genospecies and OspA serotype.
Journal of clinical microbiology - 1 Jan 1995
Wilske B, Jauris-Heipke S, Lobentanzer R, Pradel I, Preac-Mursic V, Rössler D, Soutschek E, Johnson R C
Abstract excerpt
Molecular analyses of the genes encoding OspC, a major immunodominant protein of Borrelia burgdorferi sensu lato, revealed a considerable degree of heterogeneity. In the present study, we investigated whether a similar heterogeneity of the OspC phenotype can be shown by analysis with monoclonal a...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Bacterial
- Antibodies, Monoclonal
- Antigens, Bacterial
- Antigens, Surface
- Bacterial Outer Membrane Proteins
- Bacterial Vaccines
- Borrelia burgdorferi Group
- Humans
- Lipoproteins
- Molecular Sequence Data
- Peptide Fragments