Article
[Growth inhibition of Borrelia burgdorferi sensu lato by antibodies. A contribution to understanding the pathogenesis and improving diagnosis of Lyme borreliosis].
Wiener medizinische Wochenschrift (1946) - 1 Jan 1995
Sadziene A, Barbour A G
Abstract excerpt
Phenomenon of growth inhibition of Borrelia burgdorferi sensu lato (BBSL), the agent of Lyme disease, by antiborrelial antibodies was observed and investigated. Some of the antiborrelial antibodies were bactericidal in the absence of complement and phagocytes. Based on growth inhibition phenomenon we developed and evaluated the function-oriented in vitro growth inhibition assay (GIA). GIA proved to be more...
Topics
- Animals
- Antibodies, Bacterial
- Antigens, Bacterial
- Antigens, Surface
- Bacterial Outer Membrane Proteins
- Bacterial Vaccines
- Borrelia burgdorferi Group
- Humans
- Lipoproteins
- Lyme Disease
