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Article

Essential role for OspA/B in the life cycle of the Lyme disease spirochete.

The Journal of experimental medicine - 1 Mar 2004

Yang Xiaofeng F, Pal Utpal, Alani Sophie M, Fikrig Erol, Norgard Michael V

Abstract excerpt

The molecular basis of how Borrelia burgdorferi (Bb), the Lyme disease spirochete, maintains itself in nature via a complex life cycle in ticks and mammals is poorly understood. Outer surface (lipo)protein A (OspA) of Bb has been the most intensively studied of all borrelial molecular constituents, and hence, much has been speculated about the potential role(s) of OspA in the life cycle of Bb. However, the...

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Source

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Identifiers

PMID: 14981112
DOI: 10.1084/jem.20031960
PMCID: PMC2213294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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