Article
Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype.
Mutation research - 1 Apr 1995
Santella R M, Perera F P, Young T L, Zhang Y J, Chiamprasert S, Tang D, Wang L W, Beachman A, Lin J H, DeLeo V A
Abstract excerpt
Coal tar treated psoriasis patients were used as a model population to evaluate a panel of immunoassays for monitoring exposure to benzo[a]pyrene (BP) and related polycyclic aromatic hydrocarbons (PAH). The assays included measurement of PAH diol epoxide-DNA adducts in white blood cells by competitive enzyme-linked immunosorbent assay (ELISA) with fluorescence endpoint detection, PAH-albumin adducts by...
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