Article
Polycyclic aromatic hydrocarbon-DNA and protein adducts in coal tar treated patients and controls and their relationship to glutathione S-transferase genotype.
Mutation research - 1 Apr 1995
Santella R M, Perera F P, Young T L, Zhang Y J, Chiamprasert S, Tang D, Wang L W, Beachman A, Lin J H, DeLeo V A
Abstract excerpt
Coal tar treated psoriasis patients were used as a model population to evaluate a panel of immunoassays for monitoring exposure to benzo[a]pyrene (BP) and related polycyclic aromatic hydrocarbons (PAH). The assays included measurement of PAH diol epoxide-DNA adducts in white blood cells by compet...
Topics
- Benzo(a)pyrene
- Biomarkers
- Carcinogens
- Case-Control Studies
- Coal Tar
- DNA Adducts
- Environmental Exposure
- Environmental Monitoring
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique
- Genotype
- Glutathione Transferase