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Article

Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.

The British journal of dermatology - 1 Feb 2012

Ibbotson S H, Dawe R S, Dinkova-Kostova A T, Weidlich S, Farr P M, Ferguson J, Wolf C R, Smith G

Abstract excerpt

BACKGROUND: There is marked interpatient variation in responses to psoralen-ultraviolet A (PUVA) photochemotherapy. Identification of molecular biomarkers of PUVA sensitivity may facilitate treatment predictability.The glutathione S-transferases (GSTs) influence cutaneous defence against UV radiation-induced oxidative stress and are therefore candidate biomarkers of PUVA sensitivity. Several human GSTs, including...

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Source

Identifiers

PMID: 21967523
DOI: 10.1111/j.1365-2133.2011.10661.x

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glutathione S-transferase genotype is associated with sensitivity to psoralen-ultraviolet A photochemotherapy.PMID 21967523Read ↗

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