Article
Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes.
Cancer research - 1 Aug 1993
Shields P G, Bowman E D, Harrington A M, Doan V T, Weston A
Abstract excerpt
Molecular dosimetry for polycyclic aromatic hydrocarbon-DNA adducts, genetic predisposition to cancer, and their interrelationships are under study in numerous laboratories. This report describes a modified 32P-postlabeling assay for the detection of polycyclic aromatic hydrocarbon-DNA adducts that uses immunoaffinity chromatography to enhance chemical specificity and quantitative reliability. The assay...
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