Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls.

International journal of cancer - 1 May 2002

Chen Shu-Yuan, Wang Li-Yu, Lunn Ruth M, Tsai Wei-Yann, Lee Po-Huang, Lee Chue-Shue, Ahsan Habibul, Zhang Yu-Jing, Chen Chien-Jen, Santella Regina M

Abstract excerpt

HCC is a common cancer and HBV and AFB(1) are well-documented, major risk factors. Epidemiologic studies have documented that cigarette smoking also contributes to the development of HCC. PAHs are ubiquitous environmental pollutants and products of incomplete combustion. They are present in both mainstream and sidestream cigarette smoke. PAHs are metabolically activated by phase I enzymes, including CYP1A1, into...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to DNA Adducts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione S-Transferase pi

Share to Glutathione Transferase

Share to Hepatitis B Surface Antigens

Share to Immunoenzyme Techniques

Share to Isoenzymes

Share to Polycyclic Aromatic Hydrocarbons

Source

Identifiers

PMID: 11948486
DOI: 10.1002/ijc.10291

Genes

PAH
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controls.PMID 11948486Read ↗

Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patients.Semantic proximity Read ↗

Genetic Alterations and Oncogenic Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Epidemiological characteristics and risk factors of hepatocellular carcinomaSemantic proximity Read ↗

RASSF1A hypermethylation is associated with aflatoxin B1 and polycyclic aromatic hydrocarbon exposure in hepatocellular carcinoma.Semantic proximity Read ↗

Exposure biomarkers in chemoprevention studies of liver cancer.Semantic proximity Read ↗

The interaction between alcohol consumption and GSTM1 genotype on polycyclic aromatic hydrocarbon-DNA adduct levels in breast tissue.Semantic proximity Read ↗

Molecular targets for therapy of hepatitis B virus-induced hepatocellular carcinoma.Semantic proximity Read ↗

A review of molecular mechanisms in the development of hepatocellular carcinoma by aflatoxin and hepatitis B and C viruses.Semantic proximity Read ↗

Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers.Semantic proximity Read ↗

When less is more: The association between the expression of polymorphic CYPs and AFB1-induced HCC.Semantic proximity Read ↗

Polycyclic aromatic hydrocarbon-DNA adducts in human lung and cancer susceptibility genes.Semantic proximity Read ↗

Molecular epidemiologic studies of polycyclic aromatic hydrocarbon-DNA adducts and breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.