Article
Influence of the lpr environment on the lymph node cell phenotypes in C57BL/6 nubg and nulpr chimeras.
Immunology - 1 Dec 1994
Tiberghien F, Ceredig R, Loor F
Abstract excerpt
Mice homozygous for the lpr gene show a marked lymphoproliferative syndrome. Most T cells which accumulate in their lymphoid organs belong to a fairly unusual subpopulation. Although being CD44+ T cells expressing neither CD4 nor CD8, they are CD3 T-cell receptor (TCR) alpha beta positive and express both Thy-1 and B220, the B-cell form of the CD45 marker. To support engraftment and development of transferred lpr...
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