Article
Different expression of T-cell receptor beta-chain variable region genes in lymph nodes of lpr mice with different alleles of the major histocompatibility complex.
Immunology - 1 Jun 1990
Ohga S, Yoshikai Y, Kishihara K, Matsuzaki G, Ogimoto M, Nomoto K
Abstract excerpt
In order to search for a possible role of abnormally proliferating T cells in developing autoimmune disease in lpr mice, and to define the difference of the T cells among various lpr-congeneic mice with different clinicopathological findings, the T-cell receptor (TcR) V beta gene expression in th...
Topics
- Alleles
- Animals
- Autoimmune Diseases
- Blotting, Northern
- Female
- Gene Expression
- Lupus Erythematosus, Systemic
- Lymph Nodes
- Major Histocompatibility Complex
- Mice
- Mice, Inbred C3H
- Mice, Inbred Strains