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Article

Allelic loss of chromosomes 16q and 10q in human prostate cancer.

Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 1990

Carter B S, Ewing C M, Ward W S, Treiger B F, Aalders T W, Schalken J A, Epstein J I, Isaacs W B

Abstract excerpt

Recent advances in understanding the molecular genetics of common adult tumors have indicated that multiple genetic alterations including the activation of oncogenes and the inactivation of tumor suppressor genes are important in the pathogenesis of these tumors. Loss of heterozygosity is a hallmark of tumor suppressor gene inactivation and has been used to identify chromosomal regions that contain these genes....

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Identifiers

PMID: 1978938
DOI: 10.1073/pnas.87.22.8751
PMCID: PMC55037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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