Loss of heterozygosity on chromosome 17q11-21 in cancers of women who have both breast and ovarian cancer.

doi:10.1016/0002-9378(95)90020-9

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Article

Loss of heterozygosity on chromosome 17q11-21 in cancers of women who have both breast and ovarian cancer.

American journal of obstetrics and gynecology - 1 Mar 1995

Schildkraut J M, Collins N K, Dent G A, Tucker J A, Barrett J C, Berchuck A, Boyd J

Abstract excerpt

OBJECTIVE: Our purpose was to determine the frequency of allele loss in the region of the BRCA1 gene in cancers of women who have both breast and ovarian cancer. STUDY DESIGN: Four polymorphic microsatellite markers on chromosome 17q11-21 were examined by the polymerase chain reaction in deoxyrib...

Topics

Alleles
Breast Neoplasms
Chromosomes, Human, Pair 17
Female
Genes, Tumor Suppressor
Heterozygote
Homozygote
Humans
Middle Aged
Ovarian Neoplasms

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