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Article

Identification of a megaplasmid centromere reveals genetic structural diversity within the repABC family of basic replicons.

Molecular microbiology - 1 Mar 2006

MacLellan Shawn R, Zaheer Rahat, Sartor Andrea L, MacLean Allyson M, Finan Turlough M

Abstract excerpt

The basic replication unit of many plasmids and second chromosomes in the alpha-proteobacteria consists of a repABC locus that encodes the trans- and cis-acting components required for both semiautonomous replication and replicon maintenance in a cell population. In terms of physical genetic organization and at the nucleotide sequence level, repABC loci are well conserved across various genera. As with all...

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PMID: 16468995
DOI: 10.1111/j.1365-2958.2006.05040.x

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