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Article

Gyrase-dependent stabilization of pSC101 plasmid inheritance by transcriptionally active promoters.

The EMBO journal - 1 Sept 1991

Beaucage S L, Miller C A, Cohen S N

Abstract excerpt

The pSC101 plasmid encodes a cis-acting genetic locus termed par that ensures the stable inheritance of plasmids in a population of dividing cells. In the absence of selection, par-defective plasmids are lost rapidly from the bacterial population. We report here that the stability of par-deleted pSC101 derivatives is restored by introducing certain adventitious bacterial promoters onto the plasmid. Stabilization...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 1651231
DOI: 10.1002/j.1460-2075.1991.tb07799.x
PMCID: PMC452956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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