Detection of frequent allelic loss of 6q23-q25.2 in microdissected human breast cancer tissues.

doi:10.1002/(SICI)1098-2264(199605)16:1<35::AID-GCC5>3.0.CO;2-4

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Article

Detection of frequent allelic loss of 6q23-q25.2 in microdissected human breast cancer tissues.

Genes, chromosomes & cancer - 1 May 1996

Fujii H, Zhou W, Gabrielson E

Abstract excerpt

Detection of allelic loss in human breast cancer is hindered by the fact that breast cancer tissues are frequently infiltrated by stromal and inflammatory cells. For this study, we carefully microdissected infiltrating breast cancer tumor cells from contaminating normal cells and analyzed the DNA...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Breast Neoplasms
Chromosome Deletion
Chromosomes, Human, Pair 6
Heterozygote
Humans
Immunohistochemistry
Middle Aged
Receptors, Estrogen

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