Article
Cloning and mapping of human chromosome 6q26-q27 deleted in B-cell non-Hodgkin lymphoma and multiple tumor types.
Genomics - 1 Jun 1998
Hauptschein R S, Gamberi B, Rao P H, Frigeri F, Scotto L, Venkatraj V S, Gaidano G, Rutner T, Edwards Y H, Chaganti R S, Dalla-Favera R
Abstract excerpt
Frequent deletions of the distal region on the long arm of chromosome 6 have been reported in multiple human tumors including B-cell non-Hodgkin lymphoma (B-NHL), suggesting the presence of one or more tumor suppressor genes (TSGs) at this locus. Previously, we identified a region of minimal molecular deletion at 6q25-q27 (RMD-1) in B-NHL cases. To facilitate positional cloning efforts to identify the RMD-1...
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