Article
Cloning and mapping of human chromosome 6q26-q27 deleted in B-cell non-Hodgkin lymphoma and multiple tumor types.
Genomics - 1 Jun 1998
Hauptschein R S, Gamberi B, Rao P H, Frigeri F, Scotto L, Venkatraj V S, Gaidano G, Rutner T, Edwards Y H, Chaganti R S, Dalla-Favera R
Abstract excerpt
Frequent deletions of the distal region on the long arm of chromosome 6 have been reported in multiple human tumors including B-cell non-Hodgkin lymphoma (B-NHL), suggesting the presence of one or more tumor suppressor genes (TSGs) at this locus. Previously, we identified a region of minimal mole...
Topics
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Artificial, Yeast
- Chromosomes, Human, Pair 6
- Cloning, Molecular
- Electrophoresis, Gel, Pulsed-Field
- Genes, Tumor Suppressor
- Humans
- In Situ Hybridization, Fluorescence
- Kinesins
- Loss of Heterozygosity
- Lymphoma, B-Cell
- Minisatellite Repeats