Article
At least five regions of imbalance on 6q in breast tumors, combining losses and gains.
Genes, chromosomes & cancer - 1 Jan 2000
Rodriguez C, Causse A, Ursule E, Theillet C
Abstract excerpt
The long arm of chromosome 6 is frequently rearranged in human cancer. In breast cancer, allelotyping studies have indicated the existence of three to four distinct regions of allelic imbalance. Chromosome transfer studies have shown the presence of several growth inhibiting or senescence promoting genes in the segment between 6q13 and 6q27. Moreover, results from comparative genomic hybridization (CGH) analyses...
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