Article
An extracellular domain of the beta subunit is essential for processing, transport and kinase activity of insulin receptor.
The Biochemical journal - 15 Jan 1995
Haruta T, Sawa T, Takata Y, Imamura T, Takada Y, Morioka H, Yang G H, Kobayashi M
Abstract excerpt
The extracellular portion of the insulin receptor (IR) beta-subunit has four cysteine and four asparagine residues which are potentially involved in disulphide bond formation between the alpha- and beta-subunits and N-linked glycosylation respectively. However, the function of this portion is not...
Topics
- Base Sequence
- Biological Transport
- Chromatography, Affinity
- Hexosaminidases
- Insulin
- Isotope Labeling
- Lectins
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Protein Precursors
- Protein Processing, Post-Translational
- Receptor, Insulin
- Sequence Deletion
- Signal Transduction