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Article

An extracellular domain of the beta subunit is essential for processing, transport and kinase activity of insulin receptor.

The Biochemical journal - 15 Jan 1995

Haruta T, Sawa T, Takata Y, Imamura T, Takada Y, Morioka H, Yang G H, Kobayashi M

Abstract excerpt

The extracellular portion of the insulin receptor (IR) beta-subunit has four cysteine and four asparagine residues which are potentially involved in disulphide bond formation between the alpha- and beta-subunits and N-linked glycosylation respectively. However, the function of this portion is not fully understood. In order to investigate the role of the extracellular domain of beta-subunit, we created a deletion...

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Identifiers

PMID: 7832779
DOI: 10.1042/bj3050599
PMCID: PMC1136404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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