Article
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.
The EMBO journal - 17 Jul 1995
Fernandez R, Tabarini D, Azpiazu N, Frasch M, Schlessinger J
Abstract excerpt
We report the cloning and primary structure of the Drosophila insulin receptor gene (inr), functional expression of the predicted polypeptide, and the isolation of mutations in the inr locus. Our data indicate that the structure and processing of the Drosophila insulin proreceptor are somewhat di...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cell Line
- DNA
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression Regulation, Developmental
- Genes, Insect
- Humans
- Larva
- Molecular Sequence Data
- Mutation
- Nervous System