Article
Resistance to salmonellosis in the chicken is linked to NRAMP1 and TNC.
Genome research - 1 Jul 1997
Hu J, Bumstead N, Barrow P, Sebastiani G, Olien L, Morgan K, Malo D
Abstract excerpt
Natural resistance to infection with Salmonella typhimurium in mice is controlled by two major loci, Bcg and Lps, located on mouse chromosomes 1 and 4, respectively. Both Bcg and Lps exert pleiotropic effects and contribute to cytostatic/cytocidal activities of the macrophage. Bcg encodes for a m...
Topics
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Cation Transport Proteins
- Chickens
- Chromosome Mapping
- Genetic Linkage
- Genetic Predisposition to Disease
- Immunity, Innate
- Lipopolysaccharides
- Membrane Proteins
- Mice
- Molecular Sequence Data
- Mutation
- Salmonella Infections, Animal
