Genetics of host resistance and susceptibility to intramacrophage pathogens: a study of multicase families of tuberculosis, leprosy and leishmaniasis in north-eastern Brazil.

doi:10.1016/s0020-7519(97)00175-6

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Article

Genetics of host resistance and susceptibility to intramacrophage pathogens: a study of multicase families of tuberculosis, leprosy and leishmaniasis in north-eastern Brazil.

International journal for parasitology - 1 Jan 1998

Blackwell J M

Abstract excerpt

Genetic analysis of disease phenotypes segregating in recombinant inbred, congenic and recombinant haplotype mouse strains permitted us to effectively "scan" the murine genome for genes controlling resistance and susceptibility to leishmanial infections. Five major regions were implicated which,...

Topics

Animals
Brazil
Chromosome Mapping
Female
Genetic Linkage
Genetic Predisposition to Disease
Humans
Immunity, Innate
Leishmaniasis
Leprosy
Male
Mice
Pedigree
Phenotype
Tuberculosis

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