Article
Molecular genetics of inherited susceptibility to intracellular parasites.
Behring Institute Mitteilungen - 1 Feb 1991
Schurr E, Radzioch D, Malo D, Gros P, Skamene E
Abstract excerpt
In the mouse, innate susceptibility to infection with mycobacteria is controlled by the Bcg host resistance locus. Phenotypically, the locus displays two alleles, a dominant resistance and a recessive susceptibility allele. The cell type expressing the resistance locus is the mature tissue macrop...
Topics
- Animals
- Bacterial Infections
- Chromosome Mapping
- Chromosomes, Human, Pair 2
- Female
- Genes, Dominant
- Genes, Recessive
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Macrophage Activation
- Male
