Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetics of inherited susceptibility to intracellular parasites.

Behring Institute Mitteilungen - 1 Feb 1991

Schurr E, Radzioch D, Malo D, Gros P, Skamene E

Abstract excerpt

In the mouse, innate susceptibility to infection with mycobacteria is controlled by the Bcg host resistance locus. Phenotypically, the locus displays two alleles, a dominant resistance and a recessive susceptibility allele. The cell type expressing the resistance locus is the mature tissue macrophage. We have immortalized macrophages from Bcgr and Bcgs mice and found that macrophage cell lines of Bcgr origin, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 2
Share to Genes, Dominant

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Recessive

Share to Genetic Linkage

Share to Genetic Predisposition to Disease

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1675564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetics of inherited susceptibility to intracellular parasites.PMID 1675564Read ↗

Genetic control of innate resistance to mycobacterial infections.Semantic proximity Read ↗

Immunogenetics of mycobacterial infections: mouse-human homologies.Semantic proximity Read ↗

Haplotype mapping and sequence analysis of the mouse Nramp gene predict susceptibility to infection with intracellular parasites.Semantic proximity Read ↗

Genetic control of susceptibility to mycobacterial infections.Semantic proximity Read ↗

Susceptibility to tuberculosis as a complex genetic trait: analysis using recombinant congenic strains of mice.Semantic proximity Read ↗

Population and molecular genetics of susceptibility to tuberculosis.Semantic proximity Read ↗

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.Semantic proximity Read ↗

Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis.Semantic proximity Read ↗

Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes.Semantic proximity Read ↗

Genetics of susceptibility to tuberculosis in humans.Semantic proximity Read ↗

Host genetics of mycobacterial diseases in mice and men: forward genetic studies of BCG-osis and tuberculosis.Semantic proximity Read ↗

Susceptibility to mycobacterial infections: the importance of host genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.