Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of liver tumor susceptibility in mice.

Toxicology letters - 1 Dec 1995

Dragani T A, Manenti G, Gariboldi M, De Gregorio L, Pierotti M A

Abstract excerpt

A good experimental model of genetic predisposition to hepatocellular tumors is the murine strain C3H. These tumors share morphologic similarities with human hepatocellular tumors. After a treatment with a single small dose of chemical carcinogen, the C3H mice show a high susceptibility to the growth of hepatocellular neoplastic lesions, that reach a volume > 100-fold as compared to the corresponding lesions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Rodent Diseases
Share to Phenotype
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Genes, ras

Share to Liver Neoplasms

Source

Identifiers

PMID: 8597117
DOI: 10.1016/0378-4274(95)03505-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of liver tumor susceptibility in mice.PMID 8597117Read ↗

Hepatocarcinogenesis: a polygenic model of inherited predisposition to cancer.Semantic proximity Read ↗

Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.Semantic proximity Read ↗

Genetic control of resistance to hepatocarcinogenesis by the mouse Hpcr3 locus.Semantic proximity Read ↗

Genetic dissection of murine susceptibilities to liver and lung tumors based on the two-stage concept of carcinogenesis.Semantic proximity Read ↗

Genetic control of hepatocarcinogenesis in C3H mice.Semantic proximity Read ↗

Hepatocarcinogenesis in BXH recombinant inbred strains of mice: analysis of diverse phenotypic effects of the hepatocarcinogen sensitivity loci.Semantic proximity Read ↗

Oxidative DNA damage in liver of mice with different susceptibility to hepatocarcinogenesis.Semantic proximity Read ↗

Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition.Semantic proximity Read ↗

Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors.Semantic proximity Read ↗

Polygenic control of hepatocarcinogenesis in Copenhagen x F344 rats.Semantic proximity Read ↗

Mapping of novel loci involved in lung and colon tumor susceptibility by the use of genetically selected mouse strains.Semantic proximity Read ↗

Mouse strain susceptibility to diethylnitrosamine induced hepatocarcinogenesis is cell autonomous whereas sex-susceptibility Is due to the micro-environment: analysis with C3H <--> BALB / c sexually chimeric mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.