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Article

Genetic control of polyamine-dependent susceptibility to skin tumorigenesis.

Genomics - 1 Apr 2002

Megosh Louis C, Hu Juncai, George Ken, O'Brien Thomas G

Abstract excerpt

Overexpression of an ornithine decarboxylase (ODC) transgene greatly increases the susceptibility of mouse skin to carcinogen-induced tumor development. Like many phenotypes in transgenic models, this enhanced susceptibility phenotype is strongly influenced by genetic background. We have mapped tumor-modifier genes in intraspecific crosses between transgenic K6/ODC mice on a susceptible strain background...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11944982
DOI: 10.1006/geno.2002.6736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic control of polyamine-dependent susceptibility to skin tumorigenesis.PMID 11944982Read ↗

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