Gene interaction and single gene effects in colon tumour susceptibility in mice.

doi:10.1038/ng1296-468

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Article

Gene interaction and single gene effects in colon tumour susceptibility in mice.

Nature genetics - 1 Dec 1996

van Wezel T, Stassen A P, Moen C J, Hart A A, van der Valk M A, Demant P

Abstract excerpt

To dissect the multigenic control of colon tumour susceptibility in the mouse we used the set of 20 CcS/Dem (CcS) recombinant congenic (RC) strains. Each CcS strain carries a unique, random subset of approximately 12.5% of the genome of strain STS/A (STS) on the genetic background of BALB/cHeA (B...

Topics

Animals
Colonic Neoplasms
Genetic Predisposition to Disease
Mice
Mice, Inbred BALB C
Mice, Inbred Strains

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