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Article

Gene interaction and single gene effects in colon tumour susceptibility in mice.

Nature genetics - 1 Dec 1996

van Wezel T, Stassen A P, Moen C J, Hart A A, van der Valk M A, Demant P

Abstract excerpt

To dissect the multigenic control of colon tumour susceptibility in the mouse we used the set of 20 CcS/Dem (CcS) recombinant congenic (RC) strains. Each CcS strain carries a unique, random subset of approximately 12.5% of the genome of strain STS/A (STS) on the genetic background of BALB/cHeA (BALB/c). Previously, applying a protocol of 26 injections of 1,2-dimethylhydrazine (DMH), we detected two susceptibility...

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Identifiers

PMID: 8944029
DOI: 10.1038/ng1296-468

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STS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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