Karyotypic and ras gene mutational analysis in idiopathic myelofibrosis.

doi:10.1111/j.1365-2141.1994.tb05076.x

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Article

Karyotypic and ras gene mutational analysis in idiopathic myelofibrosis.

British journal of haematology - 1 Nov 1994

Reilly J T, Wilson G, Barnett D, Watmore A, Potter A

Abstract excerpt

Karyotypic analysis was performed in a total of 69 patients with well-characterized idiopathic myelofibrosis. Karyotypic abnormalities were detected in 46% of cases examined during the chronic phase (29/63); with three abnormalities, del(13q), del(20q) and partial trisomy 1q, accounting for 75% o...

Topics

Adult
Aged
Aged, 80 and over
Bone Marrow
Chromosome Aberrations
DNA Mutational Analysis
Female
Genes, ras
Humans
Karyotyping
Male
Middle Aged
Mutation
Primary Myelofibrosis
Prognosis
Risk Factors
Survival Analysis

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