Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the P53 and RAS family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders.

Leukemia - 1 Jul 1993

Gaidano G, Guerrasio A, Serra A, Carozzi F, Cambrin G R, Petroni D, Saglio G

Abstract excerpt

We have investigated the involvement of the p53 tumor suppressor gene and RAS family proto-oncogenes in BCR/ABL-negative chronic myeloproliferative disorders (CMPD), including nine cases of myelosclerosis with myeloid metaplasia, four polycythemia vera, 10 essential thrombocythemia, one juvenile chronic myeloid leukemia, and eight BCR/ABL-negative chronic myeloid leukemia. Twenty-five samples were studied in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Genes, p53

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8321046

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the P53 and RAS family genes are associated with tumor progression of BCR/ABL negative chronic myeloproliferative disorders.PMID 8321046Read ↗

Molecular mechanisms of tumor progression in chronic myeloproliferative disorders.Semantic proximity Read ↗

The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.Semantic proximity Read ↗

p53 tumour suppressor gene and RAS oncogenes: molecular analysis in the chronic and leukaemic phases of essential thrombocythaemia.Semantic proximity Read ↗

Mutations of the N-ras gene in juvenile chronic myelogenous leukemiaSemantic proximity Read ↗

N-ras and p53 gene mutations in Japanese patients with myeloproliferative disorders.Semantic proximity Read ↗

Molecular mechanisms in the evolution of chronic myelocytic leukemia.Semantic proximity Read ↗

p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy.Semantic proximity Read ↗

Role of p53 in leukemogenesis of chronic myeloid leukemia.Semantic proximity Read ↗

Correlation between molecular and clinical events in the evolution of chronic myelocytic leukemia to blast crisis.Semantic proximity Read ↗

Molecular events in chronic myeloid leukemia progression.Semantic proximity Read ↗

Genetic analysis of chromosome 13 deletions in BCR/ABL negative chronic myeloproliferative disorders.Semantic proximity Read ↗

Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia-A Retrospective Analysis in 337 Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.