Mutations of the Kirsten-ras proto-oncogene in human preleukaemia.

doi:10.1038/330186a0

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Article

Mutations of the Kirsten-ras proto-oncogene in human preleukaemia.

Nature - 1 Jan 2000

Liu E, Hjelle B, Morgan R, Hecht F, Bishop J M

Abstract excerpt

The myelodysplastic syndrome (MDS) or preleukaemia is a haematological disorder characterized by low blood counts, bone marrow cells of abnormal appearance and progression to acute leukaemia in as many as 30% of patients. The distinctive preleukaemic and leukaemic phases of this disease make it a...

Topics

Adult
Alleles
Base Sequence
Cell Transformation, Neoplastic
Codon
Genes, ras
Humans
Male
Mutation
Preleukemia
Proto-Oncogene Mas
Proto-Oncogenes
Tumor Stem Cell Assay

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