N-RAS oncogene mutations in patients with agnogenic myeloid metaplasia in leukemic transformation.

doi:10.1016/s0145-2126(98)00059-9

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Article

N-RAS oncogene mutations in patients with agnogenic myeloid metaplasia in leukemic transformation.

Leukemia research - 1 Jul 1998

Wang J C, Chen C

Abstract excerpt

From 5% to 20% of patients with agnogenic myeloid metaplasia (AMM) will evolve into a terminal leukemic phase; N-RAS gene mutations are the most common gene abnormalities detected in patients with leukemia. The present study was designed to see if N-RAS gene mutations are associated with the leuk...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Cell Transformation, Neoplastic
Female
Genes, ras
Humans
Leukemia
Male
Middle Aged
Mutation
Primary Myelofibrosis

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