Article
N-RAS oncogene mutations in patients with agnogenic myeloid metaplasia in leukemic transformation.
Leukemia research - 1 Jul 1998
Wang J C, Chen C
Abstract excerpt
From 5% to 20% of patients with agnogenic myeloid metaplasia (AMM) will evolve into a terminal leukemic phase; N-RAS gene mutations are the most common gene abnormalities detected in patients with leukemia. The present study was designed to see if N-RAS gene mutations are associated with the leukemic transformation in AMM. Over a 9 year period, in a single institution, 43 patients with AMM were studied. Of these,...
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