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Article

Cytogenetic abnormalities and their prognostic significance in idiopathic myelofibrosis: a study of 106 cases

1 Jul 1997

Abstract excerpt

The prognostic significance of cytogenetic abnormalities was determined in 106 patients with well-characterized idiopathic myelofibrosis who were successfully karyotyped at diagnosis. 35% of the cases exhibited a clonal abnormality (37/106), whereas 65% (69/106) had a normal karyotype. Three characteristic defects, namely del(13q) (nine cases), del(20q) (eight cases) and partial trisomy 1q (seven cases), were...

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PMID: 9233570
DOI: 10.1046/j.1365-2141.1997.1722990.x

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