Article
Loss of heterozygosity at chromosome 1q loci in rat mammary tumors.
Molecular carcinogenesis - 1 Jan 1995
Gollahon L S, Chen A, Aldaz C M
Abstract excerpt
To better characterize abnormalities affecting rat chromosome 1 during mammary carcinogenesis, tumors were induced by nitrosomethylurea in F1 hybrid rats polymorphic at multiple chromosome 1 loci. By means of restriction fragment length polymorphism and microsatellite length polymorphism analyses, we observed loss of heterozygosity or allelic imbalance affecting various loci on the q arm of chromosome 1 in a high...
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