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Article

Loss of heterozygosity at chromosome 1q loci in rat mammary tumors.

Molecular carcinogenesis - 1 Jan 1995

Gollahon L S, Chen A, Aldaz C M

Abstract excerpt

To better characterize abnormalities affecting rat chromosome 1 during mammary carcinogenesis, tumors were induced by nitrosomethylurea in F1 hybrid rats polymorphic at multiple chromosome 1 loci. By means of restriction fragment length polymorphism and microsatellite length polymorphism analyses, we observed loss of heterozygosity or allelic imbalance affecting various loci on the q arm of chromosome 1 in a high...

Topics

Adenocarcinoma
Animals
Chromosome Deletion
Chromosome Mapping
Female
Genes, ras
Heterozygote
Mammary Neoplasms, Experimental
Methylnitrosourea
Mutation
Polymorphism, Genetic
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Inbred ACI

Rats, Inbred BN

Rats, Inbred BUF

Rats, Inbred Lew

Source

Identifiers

PMID: 7818765
DOI: 10.1002/mc.2940120103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7818765-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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