Article
Two distinct regions involved in 1p deletion in human primary breast cancer.
Cancer research - 1 May 1993
Bièche I, Champème M H, Matifas F, Cropp C S, Callahan R, Lidereau R
Abstract excerpt
Alteration of chromosome 1 is the most consistent cytogenetic abnormality found in human breast carcinoma. Cytogenetic studies have shown independent alterations on the two arms of chromosome 1, increased copy number of the long arm and loss of the short arm of chromosome 1. These deletions are thought to coincide with the location of tumor suppressor gene(s). We carried out deletion analysis of the 1p region by...
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