Article
Nonrandom abnormalities involving chromosome 1 and Harvey-ras-1 alleles in rat mammary tumor progression.
Cancer research - 1 Sept 1992
Aldaz C M, Chen A, Gollahon L S, Russo J, Zappler K
Abstract excerpt
Little is known about the role of chromosomal abnormalities in the widely used models of rat mammary carcinogenesis. In this study, we cytogenetically analyzed nitrosomethylurea-induced rat mammary adenocarcinomas at different time points of development. As tools to study more advanced stages of...
Topics
- Adenocarcinoma
- Alleles
- Animals
- Base Sequence
- Chromosome Aberrations
- Chromosome Disorders
- Chromosome Mapping
- Female
- Genes, ras
- Mammary Neoplasms, Experimental
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Rats
- Rats, Inbred BUF
