Article
A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors.
Molecular carcinogenesis - 1 Jan 1999
Haag J D, Brasic G M, Shepel L A, Newton M A, Grubbs C J, Lubet R A, Kelloff G J, Gould M N
Abstract excerpt
In this paper, patterns of allelic imbalances (Als) in chemically induced rat mammary, colon, and bladder tumors from (Wistar Furth x Fischer 344)F1 rats are described and compared. Male F1 rats were administered azoxymethane (AOM), and colon tumors were collected at 58 wk after treatment. Female F1 rats were given either N-nitroso-N-methylurea (NMU) or N-butyl-(hydroxybutyl)-nitrosoamine (BBN), and mammary and...
Topics
- Alleles
- Animals
- Azoxymethane
- Butylhydroxybutylnitrosamine
- Carcinogens
- Chromosome Mapping
- Codon
- Colonic Neoplasms
- Female
- Genes, ras
- Genetic Markers
- Humans
- Loss of Heterozygosity
- Male