Article
Allelic imbalance on chromosome 1 in human breast cancer. I. Minisatellite and RFLP analysis.
Genes, chromosomes & cancer - 1 Jan 1995
Loupart M L, Armour J, Walker R, Adams S, Brammar W, Varley J
Abstract excerpt
In order to characterise the role of chromosome 1 more fully in breast cancer, polymorphic markers mapping along the length of the whole chromosome were used to assess a panel of 71 tumour-lymphocyte pairs for allelic imbalance. Complex patterns of alterations were established that are consistent with cytogenetic data in the literature. Deletion mapping of individuals with loss of heterozygosity identified five...
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